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human Growthhormone (GH) is a single chain, non-saccharized, 191-amino acid hydrophilic globulin with a molecular weight of 21700Da and an isoelectric point pI of 4.9.
The cysteine residues at positions 53 and 165 and 182 and 189 were disulfide bonded.
About 75% of the growth hormone secreted by the anterior eosinophils of the pituitary gland is secreted in this molecular form, and another 5% to 10% in the form of 20kDa.
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